Table 2. Parameters for diabetic rats treated with miR-27a mimics at week 12.

Variables	DM_miR-NC (n=6)	DM_miR-27am (n=6)
Scr (μmol/l)	118.35±5.19	130.27±6.58*
Serum BUN (mmol/l)	16.79±3.37	20.58±3.13*
Blood glucose (mmol/l)	25.45±0.37	26.77±1.34
UAER (μg/min)	1.75±0.31	3.02±0.61#
UACR (μg/mmol)	26.15±2.25	60.17±3.56#
Ccr (ml/min/kg)	3.55±0.42	0.72±0.06#

Abbreviations: BUN, blood urea nitrogen; Ccr, creatinine clearance rate; DM_miR-NC, diabetic rats treated with miRNA mimics negative control; DM_miR-27am, diabetic rats treated with miR-27a mimics; Scr, serum creatinine; UACR, urine albumin to creatinine ratio; UAER, urine albumin excretion rate

*P<0.01; ^#P<0.001