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. 2017 Mar 16;8(3):e2675. doi: 10.1038/cddis.2017.81

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Copyright © 2017 The Author(s)

Cell Death and Disease is an open-access journal published by Nature Publishing Group. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Aberrant upregulated intranuclear Linc00441 reversely corrected with RB1 expression. (a) Relatively expression of Linc00441 and RB1 in the tumor tissues, corresponding adjacent tissues of HCC patients (n=80) and healthy liver tissues (n=16). Data are presented as means±S.E.M. with log-transformed and analyzed with paired Student's t-test. (b) Pearson correlation analysis between the expression of Linc00441 and RB1. (c) Antibody-labeled RB1 (green) and probe-labeled Linc00441 (red) was detected in MHCC-97H (left panel) and HepG2 (right panel). Blue 4,6-diamidino-2-phenylindole (DAPI) staining indicates nuclei. Scale was presented at lower right of the first panel each with × 400 magnification. (*P<0.05, **P<0.01)