Appendix 1—table 1.

Parameters used for simulations. For the serial, two state and multistate models, the plasticity parameter listed is the transition probability between adjacent states. For the pooled resource model, the plasticity parameters are the minimum and maximum transition probability for the constituent two-state synapses. For the cascade and non-uniform multistate models, the plasticity parameter is the ratio of adjacent transition probabilities.

DOI: http://dx.doi.org/10.7554/eLife.20147.019

Model	# states	Plasticity parameter			${\displaystyle f^{\text{dep}}}$			${\displaystyle r{t}_{\text{pre}}}$
		Pot	WT dep	DKO dep	Base	Inc	Dec
Serial	10	0.12	0.14	0.2	0.5	0.89	0.11	100
Two-state	2	0.1	0.1	0.2	0.5	0.6	0.4	5
Multistate	10	0.3	0.3	0.4	0.5	0.8	0.2	5
Pooled res.	7	0.008	[0.0006, 0.6]	[0.001, 1]	0.5	0.9	0.1	20
Cascade	14	0.386	0.398	0.466	0.478	0.63	0.002	200
Non-uni.	12	0.4	0.4	0.53	0.5	0.7	0.1	500