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. 2017 Mar 15;15(1):943. doi: 10.18549/PharmPract.2017.01.943

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Copyright: © 2017 Pharmacy Practice and The Authors

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY-NC-ND 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Network diagrams and definitions (Examples of networks geometries and evolution of statistical concepts).

First panel: Adjusted Indirect Treatment Comparison (ITC) proposed by Bucher (simple indirect comparison); Second Panel: Network meta-analysis proposed by Lumley (open loops meta-analysis); Third Panel: Mixed Treatment Comparison proposed by Lu and Ades as an improvement of Network meta-analysis from Lumley. Together, these meta-analytical process are also called “network meta-analysis” and cover direct and indirect comparisons in the same model.