Table 1. Patient demographics.
| Variables | Total No. | SERPINA3 | ||
|---|---|---|---|---|
| Low No. (%) | High No. (%) | P† | ||
| All melanomas | 366 | |||
| Age (years) | ||||
| ≤ 60 | 195 | 87 (45) | 108 (55) | 0.0636 |
| > 60 | 171 | 60 (35) | 111 (65) | |
| Sex | ||||
| Male | 216 | 95(44) | 121(56) | 0.0738 |
| Female | 150 | 52(35) | 98(65) | |
| AJCC stage | ||||
| I | 109 | 60(55) | 49(45) | 0.0003* |
| II | 119 | 45(38) | 74(62) | |
| III | 94 | 24(26) | 70(74) | |
| IV | 44 | 18(41) | 26(59) | |
| Primary melanomas | 228 | |||
| Age (years) | ||||
| ≤ 60 | 114 | 59(52) | 55(48) | 0.0841 |
| > 60 | 114 | 46(40) | 68(60) | |
| Sex | ||||
| Male | 120 | 65(54) | 55(46) | 0.0096* |
| Female | 108 | 40(37) | 68(63) | |
| Tumor thickness (mm) | ||||
| ≤ 2.00 | 118 | 64(54) | 53(46) | 0.0085* |
| > 2.00 | 110 | 41(37) | 69(63) | |
| Ulceration | ||||
| Absent | 166 | 84(51) | 82(49) | 0.0378* |
| Present | 60 | 21(35) | 39(65) | |
| Site* | ||||
| Sun-protected | 55 | 27(49) | 28(51) | 0.9025 |
| Sun-exposed | 162 | 78(48) | 84(52) | |
| Unspecified | 1 | |||
| Subtype | ||||
| Superficial spreading | 90 | 48(53) | 42(47) | 0.0682 |
| Lentigo maligna | 42 | 12(29) | 30(71) | |
| Nodular | 30 | 15(50) | 15(50) | |
| Others | 25 | 9(36) | 16(64) | |
| Unspecified | 41 | 21(51) | 20(49) | |
| Metastatic melanomas | 138 | |||
| Age (years) | ||||
| ≤ 60 | 81 | 28(35) | 53(65) | 0.2085 |
| > 60 | 57 | 14(25) | 43(75) | |
| Sex | ||||
| Male | 96 | 30(31) | 66(69) | 0.7530 |
| Female | 42 | 12(29) | 30(71) | |
†: Chi-square test.
*: Sun-protested sites: trunk, arm, leg and feet; Sun-exposed sites: head and neck.
Patient Demographics with age and sex based on NN (Normal Nevi), MIS (Melanoma in Situ), PM (Primary Melanoma) and MM (Metastatic Melanoma) types of sample. AJCC Stage is a system devised by the American Joint Committee on Cancer to determine severity of tumors in patients. N/A denoted for data not available. Asterisks indicate significant p-values at α = 0.05.