Table 1. Lung W/D ratio and SPA, IL-6 and TNF-α levels in plasma (n = 8).
Group | W/D | plasma | ||
---|---|---|---|---|
SPA(ng/L) | TNF-a (μg/L) | IL-18 (μg/L) | ||
Control Group | 3.69 ± 1.12 | 16.01 ± 1.33 | 38.02 ± 8.35 | 32.22 ± 3.71 |
GLA | 3.82 ± 2.01 | 16.41 ± 2.01 | 36.76 ± 6.72 | 31.42 ± 3.18 |
LPS | ||||
6 h | 5.55 ± 0.73a | 18.13 ± 2.53 | 106.26 ± 30.37a | 49.21 ± 6.35a |
12 h | 5.82 ± 0.94a | 22.3 ± 2.79a | 105.91 ± 28.29a | 49.37 ± 13.27a |
24 h | 5.63 ± 0.47a | 20.63 ± 3.67 a | 93.04 ± 21.66a | 42.34 ± 14.01a |
LPS+GLA | ||||
6 h | 4.31 ± 1.79b | 16.81 ± 3.34 | 58.24 ± 19.86b | 36.35 ± 27.94b |
12 h | 4.30 ± 0.67b a | 18.82 ± 1.88b | 50.67 ± 9.42b | 36.82 ± 12.56b |
24 h | 4.25 ± 0.96a | 18.43 ± 1.66b | 61.50 ± 21.82b | 39.36 ± 8.29b |
The table indicates the change of W/D, SPA, IL-18, TNF-a among the groups, compared with control group aP < 0.05, and compare with LPS group bP < 0.05.