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. 2017 Jan 27;8(12):18968–18978. doi: 10.18632/oncotarget.14859

Table 2. Univariate and multivariate analysis of overall survival in training set.

Characteristics Univariate analysis Multivariate analysis C-index AIC
β HR (95% CI) P value β HR (95% CI) P value
Age 0.203 1.225 (1.026–1.464) 0.025 0.283 1.327 (1.053–1.671) 0.016 0.528 3936.8
Gender 0.017 1.017 (0.818–1.265) 0.879 0.499 3935.5
Tumor location 0.003 1.003 (1.001–1.006) 0.004 0.516 3937.0
Macroscopic type 0.540 1.716 (1.566–1.879) < 0.001 0.257 1.292 (1.109–1.507) 0.001 0.653 3832.8
Differentiation degree 0.422 1.525 (1.352–1.720) < 0.001 0.593 3894.7
Tumor diameter 0.632 1.882 (1.721–2.058) < 0.001 0.686 3835.3
T stage 0.736 2.087 (1.889–2.306) <0.001 0.681 3780.3
N stage 0.657 1.930 (1.798–2.072) < 0.001 0.561 1.753 (1.576–1.949) < 0.001 0.736 3698.2
V stage 0.681 1.975 (1.820–2.144) < 0.001 0.340 1.405 (1.235–1.599) < 0.001 0.715 3768.2
Vessel invasion 1.087 2.966 (2.282–3.855) < 0.001 0.614 3871.8
Neural invasion 1.237 3.445 (2.395–4.955) < 0.001 0.579 3880.2

HR: Hazard ratio; CI: Confidence interval.