Table 2. Enrichment of clusters for Gene Ontology (GO) functions related to DNA damage, cell cycle, and chromosomal organization.
| Cluster # | 2 | 5 | 6 | 7 | 9 | 11 | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Genes in cluster | 28 | 109 | 37 | 67 | 59 | 17 | ||||||
| DNA repair | 5.0E-06 | ( 9 ) | 4.4E-15 | ( 29 ) | 2.2E-24 | ( 30 ) | ||||||
| nucleotide-excision repair | 1.2E-02 | ( 3 ) | 1.3E-07 | ( 8 ) | ||||||||
| double-strand break repair | 8.2E-13 | ( 16 ) | 5.3E-07 | ( 9 ) | ||||||||
| meiotic cell cycle | 1.3E-06 | ( 18 ) | 1.6E-04 | ( 11 ) | ||||||||
| DNA replication | 8.6E-02 | ( 3 ) | 1.4E-06 | ( 13 ) | 2.4E-08 | ( 12 ) | ||||||
| DNA-dependent ATPase activity | 9.8E-10 | ( 12 ) | 1.8E-02 | ( 4 ) | 9.6E-02 | ( 3 ) | ||||||
| DNA integrity checkpoint | 1.8E-10 | ( 9 ) | ||||||||||
| base-excision repair | ||||||||||||
| DNA recombination | 5.8E-10 | ( 18 ) | 1.1E-10 | ( 15 ) | ||||||||
| bypass DNA synthesis | 6.3E-02 | ( 2 ) | ||||||||||
| postreplication repair | 6.5E-03 | ( 4 ) | ||||||||||
| chromosome organization | 4.3E-03 | ( 7 ) | 2.4E-08 | ( 26 ) | 1.8E-03 | ( 9 ) | 1.6E-04 | ( 14 ) | 7.4E-02 | ( 8 ) | 8.0E-02 | ( 4 ) |
| structure-specific DNA binding | 1.9E-03 | ( 7 ) | 7.6E-06 | ( 8 ) | ||||||||
| non-recombinational repair | 7.6E-08 | ( 10 ) | 1.2E-03 | ( 5 ) | ||||||||
| damaged DNA binding | 2.7E-11 | ( 9 ) | ||||||||||
| cell division | 2.0E-02 | ( 7 ) | 5.6E-03 | ( 6 ) | ||||||||
| response to DNA damage stimulus | 2.4E-05 | ( 9 ) | 3.1E-17 | ( 34 ) | 1.1E-02 | ( 7 ) | 6.1E-23 | ( 31 ) | ||||
| recombinational repair | 5.4E-14 | ( 14 ) | 1.3E-07 | ( 8 ) | ||||||||
| SWI/SNF complex | 2.8E-03 | ( 3 ) |
P values for the indicated GO function enrichment are shown (with the corresponding number of genes in parentheses). Only clusters with significant (p<0.05) values for the indicated categories are given. Color codes for p-value: light gray, < 1.0E-5; dark grey, < 1.0E-10.