Figure 5. FAM84B upregulation does not associate with Gleason score (GS) advancement.

(A) FAM84B mRNA expression data were extracted from the Taylor dataset in the Oncomine^TM database, and were analyzed as low grade (GS6-7) or high grade (GS8-10) PCs. *p < 0.05 and **p < 0.01 in comparison to normal prostate tissues (2-tailed Student's t-test). (B) IHC staining for FAM84B in 22 primary PC tissues (Supplementary Table 1). Typical images for tumors with the indicated GS are shown. Scale bars represent 200 μm (See Supplementary Figure 5 for additional images). (C) IHC staining was quantified through ImageScope software. Average HScores ± SDs are graphed (for detailed scores, See Supplementary Table 1). Statistical analyses were performed using Student's t-test.