Table 3A. Frequency distributions of the number of risk alleles between cases and controls, and their association with PCa risk.
cases (n = 830) | controls (n= 869) | Pa | Adjusted OR (95% CI)b | |||
---|---|---|---|---|---|---|
n | % | n | % | |||
Number of risk alleles | ||||||
0 | 95 | 11.5 | 125 | 14.4 | < 0.001 | 1.00 (reference) |
1 | 175 | 21.1 | 223 | 25.7 | 0.850 | 1.09 (0.77–1.53) |
2 | 314 | 37.8 | 354 | 40.7 | 0.324 | 1.10 (0.94–1.28) |
3 | 132 | 15.9 | 106 | 12.2 | 0.009 | 1.19 (1.05–1.35) |
4 | 114 | 13.7 | 61 | 7.0 | < 0.001 | 1.29 (1.16–1.43) |
Recombined groups | ||||||
0-1 | 270 | 32.5 | 348 | 40.0 | 0.001 | 1.00 (reference) |
2-4 | 560 | 67.5 | 521 | 60.0 | 1.37 (1.12–1.68) |