Table 4. Stratification analysis of number of risk alleles and PCa risk.

Variables	Case (n = 830)		Control (n = 869)		Pa	Adjusted OR (95% CI)b
	Number of risk alleles		Number of risk alleles
	0–1	2–4	0–1	2–4
Total	270	560	348	521	0.001	1.37 (1.12–1.68)
Age
≤ 71	127	256	169	260	0.706	1.32 (0.98–1.78)
> 71	143	304	179	261	0.007	1.42 (1.08–1.88)
Smoke status
Never	112	213	157	235	0.124	1.25 (0.91–1.71)
Ever	158	347	191	286	0.004	1.47 (1.12–1.94)
Pack-years of smoking
0–20	80	149	85	147	0.703	1.15 (0.77–1.72)
> 20	78	198	106	139	< 0.001	1.89 (1.29–2.77)
Drinking status
Never	191	391	256	382	0.008	1.36 (1.07–1.73)
Ever	79	169	92	139	0.069	1.31 (0.89–1.93)
Tea drinking
Never	122	285	151	232	0.005	1.56 (1.15–2.10)
Ever	148	275	197	289	0.086	1.21 (0.92–1.59)
Family history of cancer
No	205	434	300	447	0.002	1.39 (1.11–1.74)
Yes	65	126	48	74	0.340	1.28 (0.79–2.09)
Hypertension
No	204	410	268	399	0.013	1.34 (1.06–1.69)
Yes	66	150	80	122	0.074	1.46 (0.96–2.20)
Diabetes
No	230	477	300	461	0.006	1.32 (1.06–1.64)
Yes	40	83	48	60	0.063	1.72 (0.97–3.04)

Bold values indicated significant differences between two groups.

^aTwo-sided χ² test for either genotype distributions or allele frequencies between the cases and controls. All P values were Bonferroni corrected, and statistical significance was set at P < 0.00556 (0.05/9).

^bAdjusted for age, bmi, pack-years of smoking, drinking status, tea drinking, hypertension and diabetes in logistic regression model.