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. 2016 Dec 27;8(12):19342–19353. doi: 10.18632/oncotarget.14258

Figure 3. HnRNP L knockdown inhibits the proliferation of prostate cancer cell lines via cell cycle arrest.

Figure 3

A. Ectopic expression of HnRNP-L in PC3 cells (left) and DU145 cells (right) analyzed by western blotting. GAPDH was used as a loading control. B, C and D. HnRNP-L knockdown inhibits the proliferation of PC3 and Lncap cells as detected by CCK-8 assays (B) and colony formation assays (C and D). Each bar represents the mean ± SD of three independent experiments.*:P<0.05. E and F. Flow cytometric analysis of cell cycle arrest after treatment of shRNAs and negative controls in PC3 and Lncap cell lines. Data represented as mean ± SD of three independent experiments. *:P<0.05 (vs. control).