Figure 4. MiR-150-5p is a target of ZFAS1.
A. The putative binding sites of ZFAS1 and miR-150-5p. B. The luciferase reporter plasmid containing ZFAS1 was co-transfected with miR-150-5p or miR-Control in Caov3 and SKOV3 cells. Luciferase activities were determined at 48 h after transfection. The relative luciferase activities normalized to Renilla activity.*p<0.05 compared with control cells. C. Relative expression of miR-150-5p in Caov3 and SKOV3 cells transfected with ZFAS1 siRNA. *p<0.05 compared with control cells. D. Expression levels of miR-150-5p in 66 EOC tissues relative to 10 normal epithelial tissues samples (p<0.001). E. The correlation of the expression levels of ZFAS1 and miR-150-5p (r=0.613; p<0.001).