Table 2. Univariate and multivariate analyses of E-cadherin expression in disease-free survival and overall survival.

Variable analysis	Disease-Free Survival			Overall Survival
	HR	95% CI	p	HR	95% CI	p
Univariate	N = 125			N = 125
E-cadherin	0.229	0.053–0.991	0.049	0.028	0.001–15.090	0.266
Multivariate	N = 125			N = 125
Gender	0.749	0.279–2.008	0.565	0.541	0.111–2.637	0.447
Age	0.281	0.101–0.786	0.016	0.149	0.028–0.786	0.025
Size	0.708	0.209–2.400	0.579	0.505	0.061–4.207	0.528
Stage	1.779	1.007–3.142	0.047	2.165	0.951–4.930	0.066
Necrosis	2.346	0.734–7.500	0.150	1.298	0.250–6.750	0.756
Fuhrman	1.249	0.736–2.118	0.409	1.868	0.841–4.150	0.125
E-cadherin	0.206	0.046–0.928	0.040	0.000	0.000–4.007E205	0.960

The variables were compared in the following ways: Age, ≥ 57 years vs. < 57 years; Gender, male vs. female; E-cadherin expression, positive vs. negative; size, > 5.25 vs. < 5.25; Stage, III–IV vs. I–II; Necrosis, yes vs. no; Fuhrman grade, G3-4 vs. G1-2.