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. 2017 Feb 19;8(12):19768–19779. doi: 10.18632/oncotarget.15519

Figure 1. CDCA2 is upregulated in LAC tissues and correlates with more aggressive clinical characteristics in TCGA dataset.

Figure 1

(A) CDCA2 is over-expressed in 94.7% (54 of 57) of LAC tissues compared with para-tumor normal tissues. (B and C) CDCA2 was found to be positively correlated with Ki-67 (r = 0.8189, p < 0.0001) and DNA ploidy (p < 0.0001) in LAC tissues. (D) Kaplan-Meier survival analysis indicated that higher CDCA2 expression is associated with worse overall survival in LAC patients (HR = 1.919, p = 0.0002).