Table 2. Cox regression analysis of overall survival in LAC patients in TCGA LAC dataset.

	Univariate analysis			Multivariate analysis
	HR	P value	95% CI	HR	P value	95% CI
Gender (Male vs Female)	1.125	0.498	0.800–1.581
Age (> 60 years vs ≤ 60 years)	1.267	0.211	0.874–1.835
Primary tumor size(T2–4 vs T1)	1.745	0.008*	1.155–2.637	1.169	0.506	0.738–1.851
Lymph node status(N1–3 vs N0)	2.93	< 0.001*	2.066–4.157	1.287	0.392	0.723–2.292
TNM stage(Stag II–IV vs Stage I)	3.229	< 0.001*	2.226–4.684	2.143	0.018*	1.142–4.021
CDCA2 expression(High vs Low)	1.786	< 0.001*	1.251–2.550	1.720	0.004*	1.189–2.489
Ki-67 expression(High vs Low)	1.712	0.002*	1.218–2.408	1.402	0.200	0.837–2.349

* Significant correlation,

Features with p value < 0.05 in univariate analysis were taken into multivariate analysis.