Table 4. Cox regression analysis of overall survival in LAC patients in TMA.

	Univariate analysis			Multivariate analysis
	HR	P value	95% CI	HR	P value	95% CI
Gender (Male vs Female)	0.952	0.866	0.536–1.690
Age (> 60 years vs ≤ 60 years)	1.982	0.009*	1.183–3.320	2.013	0.026*	1.089–3.724
Differentiation (Poor vs Moderate & Well)	2.594	0.001*	1.469–4.579
Primary tumor size (T2–4 vs T1)	1.106	0.710	0.649–1.887
Lymph node status (N1–3 vs N0)	2.289	0.002*	1.364–3.839	1.585	0.139	0.861–2.919
TNM stage (Stage II–IV vs Stage I)	2.365	0.001*	1.413–3.958	2.064	0.025*	1.096–3.888
CDCA2 expression (High vs Low)	2.108	0.006*	1.236–3.594	1.971	0.023*	1.100–3.533

* Significant correlation.

Features with p value < 0.05 in univariate analysis were taken into multivariate analysis.