Table 2. T cell subset densities according to pre-treatment clinical and demographic factors.
| Foxp3+ cell density | CD8+ cell density | CD3+ cell density | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Lown (%) | Highn (%) | P | Lown (%) | Highn (%) | P | Lown (%) | Highn (%) | P | ||
| Age | ≥ 65 | 24 (47) | 27 (53) | 0.560 | 24 (47) | 27 (53) | 0.560 | 20 (45) | 24 (55) | 0.353 |
| < 65 | 29 (53) | 26 (47) | 29 (53) | 26 (47) | 27 (55) | 22 (45) | ||||
| Gender | Male | 44 (57) | 33 (43) | 0.017 | 44 (57) | 33 (43) | 0.017 | 36 (55) | 30 (45) | 0.227 |
| Female | 9 (31) | 20 (69) | 9 (31) | 20 (69) | 11 (41) | 16 (59) | ||||
| Distance from anal verge | ≥ 7cm | 28 (49) | 29 (51) | 0.846 | 28 (49) | 29 (51) | 0.846 | 25 (50) | 25 (50) | 0.911 |
| < 7cm | 25 (51) | 24 (49) | 25 (51) | 24 (49) | 22 (51) | 21 (49) | ||||
| Clinical T stage | T2 | 4 (57) | 3 (43) | 0.246 | 2 (29) | 5 (71) | 0.395 | 1 (17) | 5 (83) | 0.207 |
| T3 | 40 (47) | 46 (53) | 43 (50) | 43 (50) | 39(52) | 36(48) | ||||
| T4 | 8 (73) | 3 (27) | 7 (64) | 4 (36) | 6(60) | 4(40) | ||||
| Clinical N stage | N0 | 14 (64) | 8 (36) | 0.150 | 12 (55) | 10(45) | 0.631 | 10 (48) | 11 (52) | 0.759 |
| N1-2 | 38 (45) | 44 (54) | 40 (49) | 42 (51) | 36 (51) | 34 (49) | ||||
| Clinical M stage | M0 | 47 (49) | 48 (51) | 0.742 | 47 (49) | 48 (51) | 0.975 | 41 (49) | 43 (51) | 0.714 |
| M1-2 | 6 (60) | 4 (40) | 5 (50) | 5 (50) | 5 (63) | 3 (37) | ||||
Bold text denotes significant associations (P < 0.05)