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. 2017 Feb 4;8(12):19825–19833. doi: 10.18632/oncotarget.15082

Table 1. Basic characteristics of included studies.

Study Year Country Ethnicity Cases Gender(M/F) Method Cut-off level Survivin (+)N(%) Histological type Survival analysis
Byun 2007 Korea Asian 85 63/22 IHC >10% staining 67(79) RCC OS, RFS
Parker 2008 USA Caucasian 310 185/125 IHC >2% staining 105(33.9) ccRCC CSS
Zamparese 2008 Italy Caucasian 49 37/12 IHC >5% staining 40(81.6) RCC CSS
Parker 2009 USA Caucasian 634 413/221 IHC >15% staining NA RCC CSS
Lei 2010 China Asian 75 36/39 IHC >10% staining 40(53.3) RCC OS
Baytekin 2011 Turkey Caucasian 104 NA IHC >5% staining 24(23.1) RCC CSS
Dornbusch 2013 Germany Caucasian 42 29/13 IHC NA 20(47.6) mRCC OS
Liu 2014 China Asian 90 52/38 IHC >20% staining 74(82.2) ccRCC CSS
Weber 2014 Germany Caucasian 145 88/57 IHC NA NA ccRCC CSS
Lu 2015 China Asian 98 63/35 IHC >10% staining 51(52) ccRCC OS
Shi 2015 China Asian 65 37/28 IHC >5% staining 47(72.3) ccRCC OS

IHC: immunohistochemistry; NA: not available; RCC: renal cell carcinoma; ccRCC: clear cell renal cell carcinoma; mRCC: metastatic renal cell carcinoma; OS: overall survival; CSS: cancer-specific survival; RFS: recurrence-free survival.