Table 1. Basic characteristics of included studies.
Study | Year | Country | Ethnicity | Cases | Gender(M/F) | Method | Cut-off level | Survivin (+)N(%) | Histological type | Survival analysis |
---|---|---|---|---|---|---|---|---|---|---|
Byun | 2007 | Korea | Asian | 85 | 63/22 | IHC | >10% staining | 67(79) | RCC | OS, RFS |
Parker | 2008 | USA | Caucasian | 310 | 185/125 | IHC | >2% staining | 105(33.9) | ccRCC | CSS |
Zamparese | 2008 | Italy | Caucasian | 49 | 37/12 | IHC | >5% staining | 40(81.6) | RCC | CSS |
Parker | 2009 | USA | Caucasian | 634 | 413/221 | IHC | >15% staining | NA | RCC | CSS |
Lei | 2010 | China | Asian | 75 | 36/39 | IHC | >10% staining | 40(53.3) | RCC | OS |
Baytekin | 2011 | Turkey | Caucasian | 104 | NA | IHC | >5% staining | 24(23.1) | RCC | CSS |
Dornbusch | 2013 | Germany | Caucasian | 42 | 29/13 | IHC | NA | 20(47.6) | mRCC | OS |
Liu | 2014 | China | Asian | 90 | 52/38 | IHC | >20% staining | 74(82.2) | ccRCC | CSS |
Weber | 2014 | Germany | Caucasian | 145 | 88/57 | IHC | NA | NA | ccRCC | CSS |
Lu | 2015 | China | Asian | 98 | 63/35 | IHC | >10% staining | 51(52) | ccRCC | OS |
Shi | 2015 | China | Asian | 65 | 37/28 | IHC | >5% staining | 47(72.3) | ccRCC | OS |
IHC: immunohistochemistry; NA: not available; RCC: renal cell carcinoma; ccRCC: clear cell renal cell carcinoma; mRCC: metastatic renal cell carcinoma; OS: overall survival; CSS: cancer-specific survival; RFS: recurrence-free survival.