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. 2017 Feb 13;8(12):19980–19996. doi: 10.18632/oncotarget.15301

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Copyright: © 2017 Qin et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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A. SNORA74B expression profiles in tumor cell lines (GBC-SD, SGC996, and NOZ) and non-tumor cell line H69. B. Silencing of SNORA74B gene in GBC cell lines by shRNAs. Mock: cells treated with no shRNA. sh-NC: cells treated with sh- scrambled. C. Silencing of SNORA74B gene inhibits proliferation of GBC-SD, SGC996, and NOZ cells in vitro. Effects of SNORA74B knockdown on xenograft volume and weight in vivo. GBC-SD xenografts were shown after treatment with shRNAs D. E. IHC staining of Ki67 and PHLPP in xenografts formed by SNORA74B-silenced GBC-SD cells (×200).