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. 2017 Feb 16;8(12):20092–20102. doi: 10.18632/oncotarget.15383

Figure 3. Depletion of HDAC8 compromises K-M attachments.

Figure 3

A. Representative images of K-M attachments in control and HDAC8-KD oocytes. Oocytes were immunostained with anti-α-tubulin-FITC antibody to visualize spindles, with CREST to visualize kinetochores, and counterstained with Hoechst to visualize chromosomes. Scale bar, 5 μm. B. The rate of defective K-M attachments was recorded in control and HDAC8-KD oocytes. Data were presented as mean percentage (mean ± SEM) of at least three independent experiments. Asterisk denotes statistical difference at a p < 0.05 level of significance.