Figure 5. Knockdown GFPT1 sensitized HONE1 and HK1 cells to radiation.
(A) Colony formation ability of the irradiated HONE1 and HK1 cells transfected with GFPT1 siRNA; (B) rH2AX foci formation in nuclei of NPC cells transfected with GFPT1 siRNA; (C) Representative photos showed formation of acidic vesicular organelles (AVO) of HONE1 and HK1 cells transfected with GFPT1 siRNA upon radiation treatment. *P < 0.05; **P < 0.01.