Table 2. Quantitative Parameters and ROC analysis in Recurrence and Radionecrosis.
| Recurrence (n = 32) | Radionecrosis (n = 19) | P value* | AUC | Cutoff Value | Sensitivity (%)† | Specificity (%)† | Accuracy (%)† | |
|---|---|---|---|---|---|---|---|---|
| Mean nCBV | 3.42 (±2.89) | 1.18 (±0.83) | 0.002 | 0.859 (0.732, 0.940) | 1.07 | 90.6 (29/32) | 68.4 (13/19) | 82.3 (42/51) |
| nCBV90 | 5.98 (±4.86) | 1.97 (±1.28) | 0.001 | 0.863⊙ (0.738, 0.943) | 2.07 | 87.5 (28/32) | 73.7¥ (14/19) | 82.3 (42/51) |
| proSWMRI (%) | 9.3 (±9.79) | 42.67 (±24.64) | < 0.001 | 0.900 (0.783, 0.966) | 15.76 | 75.0 (24/32) | 89.5 (17/19) | 80.3 (41/51) |
| nCBV90 + proSWMRI | 0.939⊙ (0.835, 0.987) | 71.9 (23/32) | 100 (19/19) | 82.3 (42/51) |
Note: Unless otherwise indicated, data in parentheses are 95 % confidence intervals; Abbreviations: nCBV = normalized relative cerebral blood volume, nCBV90 = the 90th percentile values of the cumulative nCBV histogram, proSWMRI = proportion of dark signal intensity on susceptibility-weighted magnetic resonance imaging sequences, ROC = receiver operating curve, AUC = area under ROC.
*The P value for the mean comparison of each parameter between two groups. The difference between the two groups was evaluated using Student's unpaired t-test.
† Sensitivity, specificity and accuracy for identification of recurrence. Numbers in parentheses are raw data.
⊙ The AUC comparison did not reach statistical significance (p = 0.175).
¥The specificity between nCBV90 and nCBV90+proSWMRI showed significant difference by the Fisher's exact test (p = 0.046).