Table 1.

Hierarchical Poisson model estimates of incidence rates of esophageal adenocarcinoma for white males, SEER 9, 1973–2012

	Model A			Model B			Model C			Model D
Fixed effects	Coefficient	SE	P	Coefficient	SE	P	Coefficient	SE	P	Coefficient	SE	P
Model for mean
Intercept	−10.317	0.240	<0.001	−12.643	0.312	<0.001	−29.762	2.385	<0.001	−31.590	3.262	<0.001
Age (linear, centered)	0.116	0.002	<0.001	0.125	0.004	<0.001	0.123	0.003	<0.001	0.120	0.003	<0.001
Age (quadratic)	−0.002	<0.001	<0.001	−0.002	<0.001	<0.001	−0.002	<0.001	<0.001	−0.002	<0.001	<0.001
Period Obesity (%)				6.101	1.082	<0.001
Cohort obesity (%)				4.582	1.455	0.002
Period mean BMI							0.453	0.070	<0.001
Cohort Mean BMI							0.267	0.087	0.002
Period median BMI										0.553	0.101	<0.001
Cohort median BMI										0.252	0.095	0.008
Variance Components	Variance	SE	P	Variance	SE	P	Variance	SE	P	Variance	SE	P
Period
Intercept	0.498	0.255	0.025	0.052	0.030	0.038	0.045	0.026	0.039	0.080	0.045	0.039
Cohort
Intercept	0.027	0.016	0.046	0.034	0.018	0.028	0.032	0.017	0.032	0.033	0.019	0.036

BMI, body mass index; SE, standard error.