TABLE 5.
Class-specific residues of the CS-4 surfacesa
| Residue no. | Residue in GI strain (ID code)
|
Residue in GII strain (ID code)
|
||||||
|---|---|---|---|---|---|---|---|---|
| NV* (A1) | Aichi (A2) | KY-89 (A3) | VA387* (A27) | Grimsby* (A26) | MXV* (A60) | MOH* (A45) | VA207* (A37) | |
| 326 | C | K | K | K | E | L | ||
| 327 | D | I | I | V | V | L | ||
| 328 | W | Q | Q | F | F | Y | ||
| 330 | I | M | M | V | V | V | ||
| 338 | S | T | T | T | N | Del | ||
| 339 | S | R | R | R | R | Del | ||
| 340 | Q | A | A | A | A | Del | ||
| 342 | Q | K | K | E | D | Del | ||
| 343 | Y | A | A | A | A | Del | ||
| 344 | D | T | T | K | V | Del | ||
| 374 | S | T | T | T | T | T | ||
| 376 | I | V | V | V | V | V | I | I |
| 378 | P | V | V | I | L | I | ||
| 379 | P | I | I | N | G | Y | ||
| 426 | P | |||||||
| 427 | G | Del | Del | Del | Del | Del | ||
| 428 | P | Del | Del | Del | Del | Del | ||
a
Class-specific residues of the putative receptor-binding surface (patch CS-4 in Table 4 corresponding to surface 7 in Table 3) of NV along with the corresponding ET-aligned residues of GI and GII norovirus strains for partition P06. Strain names and their identification (ID) codes are from Fig. 1. All residues are denoted by their one-letter amino acid codes and they are NV numbered. Blank entries indicate residues that are identical with NV. An asterisk indicates strains for which receptor-binding data are available (15). Del, deletion.