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. Author manuscript; available in PMC: 2018 May 1.
Published in final edited form as: J Autoimmun. 2017 Jan 23;79:39–52. doi: 10.1016/j.jaut.2017.01.003

Fig. 9.

Fig. 9

MC903 treatment promotes Treg expansion and attenuates disease in EAE-induced mice. Mice were treated with MC903 or vehicle (EtOH) prior to and subsequently after the induction of active EAE with MOG35–55. (A) The frequency of circulating FoxP3+ Tregs in MC903-treated mice (filled circles) and EtOH controls (open circles; n = 8 per group, p = 0.04 by Student’s t test) is shown. (B) Clinical scores for mice treated with MC903 (filled circles) and EtOH (open circles) are shown. The graph is inclusive of two separate experiments (n = 8 mice per group per experiment).