Table 3.
Correlations between change in bulbar conjunctival microvasculature velocity and DE symptoms (including ocular pain) and signs
| Continuous variables | Change in Velocity Pearson r/Spearman rho |
|---|---|
| DE symptoms | |
|
| |
| Dry eye questionnaire 5 | −0.004/−0.032 |
| Ocular surface disease index | 0.073/0.082 |
|
| |
| Ocular pain | |
|
| |
| NRS | −0.107/−0.115 |
| NPSI-Eye total | −0.216/−0.161 |
| Burning spontaneous pain | −0.204/−0.183 |
| Wind hyperalgesia | −0.268*/−0.224 |
| Light allodynia | −0.170/−0.151 |
|
| |
| Ocular signs | |
|
| |
| Osmolarity† | −0.172/−0.251 |
| Tear break up time† | −0.062/−0.078 |
| Corneal staining† | −0.102/−0.088 |
| Schirmer’s test † | 0.046/0.062 |
| Meibum quality† | −0.153/−0.125 |
| Eyelid vascularity† | −0.132/−0.076 |
|
| |
| Corneal sensitivity | |
|
| |
| Detection threshold† | −0.003/−0.076 |
| Pain threshold† | −0.070/−0.061 |
| Pain minus detection threshold† | −0.072/−0.068 |
NRS=numerical rating scale, average ocular pain intensity, 1 week recall; NPSI-Eye=neuropathic pain symptom inventory modified for the eye;
*
p value <0.05;
†
Analysis performed on value from right eye as functional slit lamp imaging was performed on right eye.