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Proliferation response of ILN lymphocytes or genital tract lymphocytes (GT) to HIV-1 Ag and PHA in naïve mice (PBS) or mice immunized with HIV-1 Ag alone, HIV-1 Ag plus CpG, or control non-CpG ODN. Data are the mean values of triplicate samples, and each group was composed of five mice. Proliferation of lymphocytes from HIV-1 Ag plus CpG was significantly greater than that of lymphocytes from mice that were immunized with PBS (P < 0.01).
