Table 2. GO annotation enrichment.
| Category | Ontology | GO ID | In Category from Cluster | Intersection | Category Size | p-Value |
|---|---|---|---|---|---|---|
| Hydrogen ion transmembrane transporter activity | Molecular function | GO:0015078 | VMA9 VMA3 VMA16 VMA11 | 4 | 15 | 1.62E−05 |
| Amino acid binding | Molecular function | GO:0016597 | ILV6 URA2 | 2 | 4 | 6.94E−04 |
| ATP hydrolysis coupled proton transport | Biological process | GO:0015991 | VMA9 VMA3 VMA16 VMA11 | 4 | 17 | 2.779E−05 |
| Histone acetylation | Biological process | GO:0016573 | TAF5 TAF12 SPT20 TAF14 HFI1 | 5 | 42 | 8.327E−05 |
| Vacuolar acidification | Biological process | GO:0007035 | VMA9 VMA3 VMA16 VMA11 | 4 | 26 | 1.61E−04 |
| Transcription, DNA-dependent | Biological process | GO:0006351 | PDR3 RRN6 RXT2 TAF5 RPN4 TAF12 PCF11 GCN4 RPC10 NPL6 POP2 SPT20 TAF14 HFI1 FHL1 | 15 | 540 | 5.83E−04 |
| Glycogen metabolic process | Biological process | GO:0005977 | REG1 GLC7 BMH1 | 3 | 16 | 6.29E−04 |
| RNA polymerase II transcriptional preinitiation complex assembly | Biological process | GO:0051123 | TAF5 TAF12 TAF14 | 3 | 16 | 6.29E−04 |
| Regulation of carbohydrate metabolic process | Biological process | GO:0006109 | REG1 GLC7 | 2 | 4 | 6.94E−04 |
| Regulation of transcription, DNA-dependent | Biological process | GO:0006355 | PDR3 RRN6 RXT2 TAF5 RPN4 TAF12 PCF11 GCN4 NPL6 POP2 SPT20 TAF14 HFI1 FHL1 | 14 | 507 | 9.70E−04 |
| Proton transport | Biological process | GO:0015992 | VMA9 VMA3 VMA16 VMA11 | 4 | 41 | 9.71E−04 |
| Proton-transporting V-type ATPase, V0 domain | Cellular component | GO:0033179 | VMA9 VMA3 VMA16 VMA11 | 4 | 5 | 6.45E−08 |
| Vacuolar proton-transporting V-type ATPase, V0 domain | Cellular component | GO:0000220 | VMA9 VMA3 VMA16 VMA11 | 4 | 7 | 4.44E−07 |
| SLIK (SAGA-like) complex | Cellular component | GO:0046695 | TAF5 TAF12 SPT20 HFI1 | 4 | 17 | 2.78E−05 |
| Proton-transporting two-sector ATPase complex, proton-transporting domain | Cellular component | GO:0033177 | VMA3 VMA16 VMA11 | 3 | 7 | 4.22E−05 |
| SAGA complex | Cellular component | GO:0000124 | TAF5 TAF12 SPT20 HFI1 | 4 | 20 | 5.52E−05 |
| Transcription factor TFIID complex | Cellular component | GO:0005669 | TAF5 TAF12 TAF14 | 3 | 15 | 5.15E−04 |
| Intracellular | Cellular component | GO:0005622 | RPN4 VMS1 RPS13 RPL37B FUR1 MRT4 RNA14 RPS7A RPS30B RPS6A RPL33A RTC6 | 12 | 381 | 7.53E−04 |
Overrepresented biological processes for all genes resulting in haploinsufficiency on SMM media according to the FunSpec program, using a p-value cutoff of 0.001 (Robinson et al. 2002). The genes identified in this screen are listed (In Category from Cluster).