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. 2017 Feb 24;7(4):1287–1299. doi: 10.1534/g3.117.039784

Table 2. SNP-based maternal and fetal heritability for polybrominated diphenyl ethers (PBDEs) and 2,2′,4,4′,5,5′-hexabromobiphenyl (BB-153) in maternal serum.

Maternal Genetics Fetal Genetics
Compound h2g SE P-Value h2g SE P-Value
Persistent pesticides
 p,p′-DDE 0 0.32 NS 0 0.36 NS
 T-NONA 0 0.35 NS 0 0.37 NS
Polybrominated diphenyl ethers and biphenyls
 BB-153 0.93 0.31 4.5 × 10−3 0.98 0.33 4.0 × 10−3
 BDE-28 0.53 0.33 NS 0.82 0.34 1.3 × 10−2
 BDE-47 0.73 0.31 1.6 × 10−2 0.99 0.31 1.6 × 10−3
 BDE-99 0.39 0.33 NS 0.66 0.34 2.3 × 10−2
 BDE-100 0.93 0.29 1.7 × 10−3 0.99 0.32 7.2 × 10−5
 BDE-153 0.79 0.3 5.4 × 10−3 0.99 0.31 4.7 × 10−4
 Sum PBDE 0.77 0.31 8.3 × 10−3 0.91 0.33 5.2 × 10−3
Polychlorinated biphenyls
 PCB28 0 0.32 NS 0 0.36 NS
 PCB99 0 0.35 NS 0.06 0.37 NS
 PCB118 0.07 0.34 NS 0 0.38 NS
 PCB153 0.36 0.32 NS 0.58 0.34 4.54 × 10−2
 PCB170 0.39 0.33 NS 0.37 0.36 NS
 PCB180 0.15 0.32 NS 0.1 0.35 NS
 PCB187 0.42 0.33 NS 0.47 0.36 NS
 PCB194 0 0.34 NS 0 0.37 NS
 PCB199 0.38 0.32 NS 0.17 0.36 NS
 PCB138/158 0.44 0.31 NS 0.57 0.34 4.58 × 10−2
 PCB196/203 0.12 0.33 NS 0 0.36 NS
 Sum PCB 0 0.36 NS 0.09 0.38 NS

h2g, proportion of genetic variance on the total phenotypic variance; SE, standard error; NS, not significant.