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. 2017 Feb 24;7(4):1287–1299. doi: 10.1534/g3.117.039784

Table 3. Significant genetic correlation across covariate-adjusted organohalogen serum levels and corresponding linear correlation.

Maternal Genetics Fetal Genetics M/F rg
Compound Compound N rg (SE) rres rg ≠ rres Pa N rg (SE) P-Valuea Mrg ≠ Frg Pb
BDE-28 BDE-100 698 0.92*** (0.08) 0.77*** <0.01 649 NC ND ND
BDE-28 BDE-153 697 0.34*** (0.29) 0.56*** 2.1 × 10−7 648 0.66*** (0.21) 3.4 × 10−3 1.1 × 10−15
BDE-47 BDE-99 741 0.98*** (0.04) 0.93*** <0.01 688 NC ND ND
BDE-47 BDE-100 750 1.00*** (0.04) 0.93*** <0.01 697 NC ND ND
BDE-47 BDE-153 749 0.61* (0.18) 0.65*** NS 696 0.77*** (0.09) 3.4 × 10−6 3.6 × 10−9
BDE-99 BDE-100 741 0.99*** (0.07) 0.88*** <0.01 688 NC ND ND
BDE-99 BDE-153 740 0.34*** (0.31) 0.60*** 9.7 × 10−12 687 0.66*** (0.22) NS 2.2 × 10−16
BDE-100 BDE-153 749 0.64*** (0.16) 0.82*** 1.4 × 10−14 696 NC ND ND
PCB180 PCB138/158 752 1.00*** (0.40) 0.81*** <0.01 698 NC ND ND
PCB180 PCB187 714 0.80*** (0.33) 0.86*** 2.4 × 10−4 664 NC ND ND

rg, genetic correlation; SE, standard error; rres, significant Spearman’s linear correlation across residual congener levels after covariate adjustment; P, P-value; M/F, maternal/fetal; NS, not significant; NC, not converged; ND, not done. *** P < 0.001, ** P < 0.01, * P < 0.05.

a

Fisher’s z transformation test between residual and genetic correlation coefficients.

b

Fisher’s z transformation test between maternal genetic and fetal genetic correlation coefficients.