Fig. 4. Immunohistochemical localization of ionized calcium-binding protein-1 (Iba-1) in the spinal cords of normal control, vehicle-treated, and lithium-treated rats (A). Semi-quantitative analysis of Iba-1 immunoreactivity in normal control and vehicle- and lithium-treated rats with experimental autoimmune encephalomyelitis (EAE) on day 13 postimmunization (PI) (B). Counterstained with hematoxylin. Values are presented as mean±SE. ^**P<0.01 vs. normal controls (n=5 per group), ^##P<0.01 vs. vehicle treatment. Scale bars=200 µm (A).