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. 2017 Mar 29;50(1):48–59. doi: 10.5115/acb.2017.50.1.48

Table 1. p-GSK-3β immunoreactivity in the spinal cords of control and EAE-affected ratsa).

Cell type Control EAE
Normal CFA control Paralysis stage Recovery stage
G.1 G.3 R.0
Inflammatory cellsb) ND ND + + +
Astrocytes +++ +++ +++ + +++
Neurons + + + + +
Ependymal cells + + + + +
Vascular endothelial cells +++ +++ +++ +++ +++

p-GSK-3β, phosphorylated glycogen synthase kinase-3β; EAE, experimental autoimmune encephalomyelitis; CFA, complete Freund's adjuvant; ND, inflammatory cells were not detected in the spinal cord; +, weak; ++, moderate; +++, strong. a)Three blind observers examined three sections from each of five animals. b)Inflammatory cells included p-GSK-3β-positive T cells and macrophages.