Table 4.

ROC analysis

Reader	MP-MRI	MP-MRI + RSI	P*	RSI	PΦ
Sextant-based analysis
All PCa
1	0.63 (0.65)	0.68 (0.70)	<0.001	0.61 (0.60)	0.39
2	0.58 (0.60)	0.64 (0.68)	<0.001	0.63 (0.64)	<0.001
3	0.61 (0.63)	0.66 (0.68)	0.001	0.58 (0.58)	0.08
Combined	0.61 (0.63)	0.66 (0.69)	<0.001	0.61 (0.61)	0.85
High-grade PCa
1	0.71 (0.69)	0.80 (0.79)	0.01	0.73 (0.69)	0.62
2	0.66 (0.66)	0.75 (0.77)	0.01	0.74 (0.72)	0.03
3	0.72 (0.72)	0.79 (0.78)	0.04	0.66 (0.62)	0.08
Combined	0.70 (0.69)	0.78 (0.78)	<0.001	0.71 (0.68)	0.62
Hemigland-based analysis
All PCa
1	0.70 (0.71)	0.71 (0.72)	0.47	0.65 (0.67)	0.13
2	0.63 (0.65)	0.69 (0.71)	<0.001	0.67 (0.69)	0.10
3	0.64 (0.66)	0.69 (0.69)	0.09	0.62 (0.63)	0.48
Combined	0.66 (0.68)	0.70 (0.71)	0.001	0.65 (0.66)	0.64
High-grade PCa
1	0.82 (0.81)	0.85 (0.84)	0.4	0.82 (0.80)	0.97
2	0.75 (0.75)	0.83 (0.85)	0.1	0.82 (0.79)	0.14
3	0.80 (0.79)	0.85 (0.85)	0.22	0.76 (0.77)	0.45
Combined	0.79 (0.78)	0.85 (0.85)	0.04	0.80 (0.79)	0.77

Data presented are area under the ROC curves (AUC). Data in parentheses represent calculations based on prostatectomy cases alone

^*Represents comparison between MP-MRI and MP-MRI plus RSI AUC

^ΦRepresents comparison between MP-MRI and RSI AUC