Table 2.
Analysis of mitotic abnormalities in fas mutants.
| Genetic background | Metaphase | Anaphase | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| n | I | % | II | % | III | % | n | IV | % | |
| WT | 104 | 0 | 0.00 | 0 | 0.00 | 0 | 0.00 | 100 | 0 | 0.00 |
| fas1-4 | 76 | 10 | 13.16 | 8 | 10.53 | 2 | 2.63 | 102 | 10 | 9.80 |
| fas2-1 | 82 | 11 | 13.41 | 9 | 10.98 | 2 | 2.44 | 104 | 10 | 9.62 |
| fas1-4 dmc1-2 | 86 | 11 | 12.79 | 9 | 10.47 | 2 | 2.33 | 110 | 10 | 9.09 |
| fas1-4 rad51-3 | 74 | 18 | 24.32 | 10 | 13.51 | 8 | 10.81 | 108 | 22 | 20.37 |
| fas1-4 rad51-2 | 79 | 22 | 27.85 | 12 | 15.19 | 10 | 12.66 | 101 | 26 | 23.76 |
n, total cells analyzed; I, number of cells with at least a dicentric chromosome; II, number of cells with dicentric chromosomes; III, number of cells with tricentric or more fused chromosomes; IV, number of cells with either at least one anaphase bridge or a chromosome fragment.