Table 5.
MICs of beta-lactams against F. tularensis.
| Reference | Origin | Nb of strains Type/biovar | MIC range (mg/L) | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| AMP | AMC | PIP/TAZ | CAZ | COX | FEP | IMI | MER | AZT | |||
| BROTH MICRODILUTION | |||||||||||
| Georgi et al., 2012 | Europe | 69 B | 64->64 | >32 | 16->16 | ||||||
| E-TEST | |||||||||||
| Hotta et al., 2013 | Japan | 34 B | 0.047->256 | 0.047->32 | 0.094->32 | 0.75->256 | |||||
| Yeşilyurt et al., 2011 | Turkey | 39 B biovar II | >256 | >256 | >256 | >256 | >256 | >256 | >32 | ||
| Tomaso et al., 2005 | Austria | 50 B biovar II | >256 | >256 | >256 | >32 | >32 | 0.5->32 | 1.5->32 | >256 | |
| Ikäheimo et al., 2000 | Finland | 38 B | >256 | >256 | >32 | >32 | >32 | ||||
| Velinov et al., 2011 | Bulgaria | 21 B biovar II | >256 | 2-4 | |||||||
| AGAR DILUTION | |||||||||||
| Scheel et al., 1993 | Scandinavia | 20 B | >32 | >32 | >32 | >32 | |||||
* if available, MIC90 value corresponded every time to the highest value of MIC range. AMP, Ampicillin; AMC, Amoxicillin/Clavulanate; PIP/TAZ, Piperacillin/tazobactam; CAZ, Ceftazidime; COX, Ceftriaxone; FEP, Cefepime; IMI, Imipenem; MER, Meropenem; AZT, Aztreonam.