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. 2017 Apr 11;8:608. doi: 10.3389/fmicb.2017.00608

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Copyright © 2017 Choo, Trim, Leong, Abell, Brune, Jeffries, Wesselingh, Dear, Snel and Rogers.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Fecal metabolome analysis of C57BL/6J mice between two animal facilities. Unsupervised PCA analysis of fecal samples of C57BL/6J mice from two different animal facilities in the (A) positive- and (B) negative ion mode. The open and closed symbols represent female and male mice, respectively. S-plots were generated from OPLS-DA analysis of (C) positive and (D) negative markers, with the discriminant markers between the groups as labeled (Model fit: R²Y = 0.91, Q² = 0.66 for positive ionization mode and R²Y = 0.96, Q² = 0.83 for negative ionization mode).