Figure 6.
Salmonella adapts to the iron-restricted myeloid compartment of Hfe−/− mice. The expression of bacterial iron metabolic genes in the spleen was measured by qPCR. Expression of iroN (A), fepA (B), cirA (C), iroC (D), feoB (E), and sitB (F) was determined relative to the housekeeping gene gyrB. Data were compared by means of ANOVA with Tukey's post hoc test. Values are depicted as lower quartile, median and upper quartile (boxes), and minimum/maximum ranges and statistical significances are indicated. n = 14–17 per group.