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. 2015 Jun 11;5:10394. doi: 10.1038/srep10394

Figure 5. Influence of protein size on diffusion coefficients in simulations.

Figure 5

Simulations of membrane protein diffusion at protein densities of 3100 μ m-2 and 6200 μ m-2 (open circles and squares, respectively) reveal a distinct reduction of the diffusion coefficient with varying lengths of the protein soluble domain, LP. Error bars are smaller than symbol size. Empirically, the gross tendency is well described by a scaling Inline graphic (dashed line). Simulation data are in agreement with the corresponding experimental data for VSG proteins at 9 nm spacing (red filled circles). Inset: Snapshot of the simulation. For better visibility water beads are not shown, and periodic images of simulation boxes are displayed.