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. 2017 Mar 3;6(4):730–738. doi: 10.1002/cam4.1005

Table 4.

Correlation between malignant transformation and the combination of SMAD4 expression and lymphocyte infiltration in 150 oral leukoplakia patients

Characteristics Total Malignant transformation P‐value
Yes n (%) No n (%)
150 23 (15.3) 127 (84.7)
SMAD4‐low and lymphocyte infiltration‐high 54 16 (29.6) 38 (70.3) 0.00027a
Others 96 7 (7.3) 89 (92.7)

The chi‐square test was used to examine the correlation between malignant transformation and the combination of SMAD4 expression and lymphocyte infiltration in 150 OL patients.

a

< 0.01.