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. 2017 Mar 23;6(4):834–844. doi: 10.1002/cam4.1040

Figure 4.

Figure 4

GOLPH3 induces EMT through the Wnt/β‐catenin signaling pathway. (A) Western blot analysis showed that silencing GOLPH3 expression in HEY and SKOV3 cell lines decreased β‐catenin, cyclin D1, and C‐myc expression, which was restored via increasing GOLPH3 expression in HO8910 cell line. Expression levels of GOLPH3, EMT‐related markers, and Wnt/β‐catenin target genes in the different cells following treatment with 10 μmol/L XAV939 (B) or 20 mmol/L LiCl (C) for 24 h were measured using western blotting. The β‐actin was used as the loading control.