Table 2.

Significant N‐glycans and their optimal cutoff values associated with GCT detection, IGCCC risk classification (intermediate or poor risk), and progression

Diagnosis	AUC	P	95% CI	Cut off value
m/z 2379	0.84	<0.001	0.76–0.91	1.4280
m/z 2337	0.83	<0.001	0.75–0.90	1.3975
m/z 1709	0.78	<0.001	0.69–0.87	1.5255
m/z 3865	0.78	<0.001	0.68–0.88	1.1945
m/z 3195	0.77	<0.001	0.67–0.86	1.4375
m/z 2890	0.74	<0.001	0.65–0.84
m/z 3719	0.73	<0.001	0.64–0.82
m/z 3414	0.72	<0.001	0.63–0.81
m/z 3560	0.72	<0.001	0.60–0.83
m/z 2011	0.71	<0.001	0.62–0.80
m/z 3049	0.70	<0.001	0.61–0.80
Advanced disease
m/z 3560	0.75	0.020	0.56–0.93
m/z 3109	0.74	0.026	0.56–0.92
m/z 2525	0.73	0.031	0.58–0.88
m/z 3865	0.72	0.037	0.52–0.93
m/z 2890	0.71	0.045	0.53–0.90
m/z 3195	0.70	0.055	0.51–0.89
Progression
m/z 2890	0.81	0.028	0.68–0.93	2.1255
m/z 3195	0.77	0.050	0.60–0.95	2.8215
m/z 3865	0.74	0.087	0.49–0.99	2.6665
m/z 3560	0.76	0.065	0.56–0.96	2.8720
N‐glycan score
Diagnostic	0.87	<0.001	0.81–0.94	2.5
Prognostic	0.89	0.005	0.78–1.00	3.5

AUC, area‐under‐the‐curve; 95% CI, 95% confidence interval.