Table 1.
The tumor parameters in TH treated groups compared with untreated tumor bearing negative control
| Groups | |||||
|---|---|---|---|---|---|
| Tumor | 1 -ive control |
2 (0.2 g/kg TH) |
3 (1.0 g/kg TH) |
4 (2.0 g/kg TH) |
p value |
| aIncidence (%) | 100 | 80 | 80 | 70 | 0.406 |
| b Latency (days) | 51.5 (14.75) | 75.5 (29.75) | 76.5 (19.25) | 74 (23) | 0.015 |
| b Multiplicity | 4 (2.25) | 2.5 (2.75) | 3 (2.5) | 2 (2) | 0.190 |
| b Size (cm3) | 1.47 (2.78) | 0.26 (0.86) | 0.38 (1.48) | 0.60 (1.297) | 0.000 |
| b Weight (g) | 3.23 (7.23) | 1.23 (5.23) | 1.17 (2.50) | 1.27 (2.97) | 0.005 |
aFisher Exact test. Values are statistically significant when p ≤ 0.05
bKruskal-Wallis test. The data are expressed as median interquartile range (IqR) values. Values are statistically significant when p ≤ 0.05. aTumor incidence = the percentage of tumor-bearing rats in the group; bTumor latency = the duration in days for the first palpable tumor to develop after MNU administration; bMultiplicity = No. of tumors developed. –ve control is untreated tumor bearing negative control