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. 2017 Apr 11;16:64. doi: 10.1186/s12944-017-0450-5

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Liver desaturase activities and expression and liver SREBP-1c expression and DNA-binding activity from control mice and high fat diet (HFD) fed mice receiving hydroxytyrosol (HT) supplementation. a Δ-5 desaturase activity; b, Δ-6 desaturase activity; c, Δ-5 desaturase mRNA expression; d, Δ-6 desaturase mRNA expression; e, SREBP-1c mRNA expression; and f, SREBP-1c DNA binding activity. Values represent means ± SEM for 12–14 mice per experimental group. Significant differences between the groups are indicated by the letter identifying each group (one-way ANOVA and Newman-Keuls´ post-test; p < 0.05)