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. 2017 Apr 11;17:28. doi: 10.1186/s12905-017-0386-y

Table 3.

Association analysis results for unadjusted and adjusted models of T2D exposure and UF risk limiting to subjects on specific treatments

N Crude Adjusted
ORT2D 95% CI P ORT2D 95% CI P
Lower Upper Lower Upper
All Races
 T2D (diabetics on Metformin) 3,435 1.12 0.84 1.48 0.450 0.77 0.56 1.05 0.096
 T2D (diabetics on Thiazolidinedione) 3,208 1.36 0.86 2.08 0.161 0.91 0.56 1.48 0.708
 T2D (diabetics on insulin) 3,481 0.71 0.52 0.97 0.032 0.50 0.35 0.70 5.10×10 −5
European American
 T2D (diabetics on Metformin) 2,250 0.97 0.65 1.44 0.863 0.70 0.45 1.08 0.104
 T2D (diabetics on Thiazolidinedione) 2,084 1.43 0.85 2.43 0.181 0.91 0.51 1.64 0.757
 T2D (diabetics on insulin) 2,292 0.60 0.38 0.95 0.020 0.42 0.26 0.68 3.54×10 −4
African American
 T2D (diabetics on Metformin) 755 1.07 0.68 1.69 0.760 0.78 0.47 1.28 0.329
 T2D (diabetics on Thiazolidinedione) 669 1.24 0.56 2.76 0.597 0.77 0.32 1.90 0.581
 T2D (diabetics on insulin) 764 0.76 0.47 1.22 0.260 0.60 0.36 1.01 0.055

T2D type 2 diabetes, BMI body mass index, OR Odds ratio, CI 95% confidence interval; Bold indicates models with p < 0.05; Adjusted models use age (continuous), BMI (continuous); Bold indicates models with p < 0.05; N-samples size of total number of cases and controls within each drug category