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. 2017 Apr 11;16:47. doi: 10.1186/s12933-017-0525-7

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Intravenous insulin tolerance test (IVITT) in control, HFD, and metformin- and sulodexide-treated rats. a Glucose level was corrected for baseline glucose level and time indicates the time after glucose infusion. No differences in glucose level were observed between control rats (n = 9) HFD rats (n = 9), HFD rats that received metformin (n = 9) and HFD rats treated with sulodexide (n = 6). Ventricular tissues (b), gastrocnemius muscle (c) and soleus muscle (d) were isolated at t = 5 and t = 30 min (n = 3 per time point) after the insulin injection. For all isolated tissues, representative Western Blots are shown. Data are expressed as mean ± SEM, *p < 0.05 vs. control group. ^#p < 0.05 vs. HFD group