Table 2.
Cycles | Frequency | Days |
---|---|---|
1–2 | Every 14 days | D 1: paclitaxel 250 mg/m2 IV over 24 hours D 2–4: ifosfamide 2000 mg/m2 IV + mesna support D 4–14: GCSF 10 mcg/kg per day D 11–14: stem cell collection (28×106/kg CD34+ cells collected) |
3–5 | Every 21 days | D 1–3: carboplatin AUC = 8 IV + etoposide 400 mg/m2 IV D 5: stem cell infusion (9.65×106/kg CD34+ cells with each cycle) D 3–21: GCSF 10mcg/kg per day |
AUC area under the concentration-time curve, D days, GCSF granulocyte-colony stimulating factor, IV intravenous