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. 2017 Apr 8;9(10):510–518. doi: 10.4254/wjh.v9.i10.510

Table 1.

Population characteristics

Total cohort (n) Overt HE1 (n) No HE1 (n)
Demographics 165 88 77
Gender
Male 119 68 51
Female 46 20 26
Mean age (years ± SD) 53 ± 8 52 ± 7 54 ± 8
Primary indication for liver transplantation
Viral hepatitis 91 52 39
Alcoholic cirrhosis 23 18 5
Cholestatic disease (PBC, PSC, autoimmune) 30 10 20
Non-alcoholic steatohepatitis 7 6 1
Other 14 2 12
Ethnicity
Caucasian 130 75 55
Asian 22 6 16
Middle Eastern 8 4 4
Other 5 3 2
Clinical characteristics
CTP score mean ± SD 9 ± 2.5 11 ± 1.7a 7 ± 2a
CTP stage
A 41 0a 41a
B 47 22 25
C 77 66a 11a
Ascites
None 51 7a 44a
Medically controlled 54 36a 18a
Poorly controlled 60 45a 15a
BMI (kg/m2 ± SD) 27.4 ± 5.2 28.7 ± 5.4a 25.7 ± 4.2a
Nutritional status 104 65 39
SGA: A (well nourished) 12 9 3
SGA: B (moderately malnourished) 65 40 25
SGA: C (severely malnourished) 27 16 11
Biochemical characteristics
25-OHD (vitamin D) (nmol/L) mean ± SD 36 ± 15 30 ± 13a 42 ± 16a
MELD score mean ± SD 17.1 ± 6.8 19.9 ± 6. 5a 13.9 ± 5.7a
Bilirubin (μmol/L) mean ± SD 114 ± 152 141 ± 167a 83 ± 128a
Creatinine (μmol/L) mean ± SD 84 ± 50 85 ± 35a 83 ± 63
Albumin (g/L) mean ± SD 33 ± 6 31 ± 5a 35 ± 6a
INR mean ± SD 1.6 ± 0.5 1.8 ± 0.6a 1.3 ± 0.3a
Sodium (mmol/L) mean ± SD 136 ± 5 135 ± 5a 138 ± 4a
Zinc (μmol/L) mean ± SD 8 ± 4 8 ± 3a 10 ± 5a
a

P < 0.05.

1

Unless otherwise indicated there is no significant difference between HE and no HE. 25-OHD: 25-hydroxyvitamin D; HE: Hepatic encephalopathy; CTP: Child Turcotte Pugh; BMI: Body mass index; SGA: Subjective nutritional assessment; MELD: Model for end stage liver disease; INR: International normalized ratio.