TABLE 2.
Effect of gangliosides on infection of R− cells by polyomavirus and SV40
| Cell line | % LT antigen positivea
|
|||
|---|---|---|---|---|
| Polyomavirus
|
SV40
|
|||
| −GD1a | +GD1a | −GM1 | +GM1 | |
| RAG-1 | 0 | 8 ± 1 | 0 | 1.4 ± 0.5 |
| A1-1 | 1.1 ± 1 | 24 ± 4 | 3.1 ± 0.5 | 38 ± 3.5 |
| A2855 | 0 | 12 ± 1.5 | 6 ± 1.2 | 30 ± 1 |
a
Cells were infected at an MOI of ∼200 and were fixed 32 h postinfection and analyzed for LT antigen expression by indirect immunofluorescence; values indicate the percentage of total cells that were LT antigen positive. Each experiment was performed three times. The data presented are an average of the three experiments.