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. 2004 Dec 20;102(1):244–249. doi: 10.1073/pnas.0408487101

Fig. 3.

Fig. 3.

Nrf2-/- mice are more vulnerable to 3NP in vivo. 3NP was administered (n = 6 for Nrf2+/+ and Nrf2+/-; n = 8 for Nrf2-/-). (A and B) Latency to fall on rotarod (A) and weight loss as a percentage of starting weight (B) were measured 4 h after the final injection. (C) Cresyl violet (Left) and Fluorojade-B (Right) were used to visualize lesions. (D) Average lesion volume was calculated on sections 200 μm apart. All data are average ± SEM. *, P < 0.05 compared with WT mice; **, P < 0.01 compared with WT and heterozygous mice.